Pro Drop (UV-Vis Microvolume NanoDrop)

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The Denagene Tajhiz Pro Drop is an advanced UV-Vis microvolume spectrophotometer designed for high-throughput laboratories and sensitive molecular workflows—where accuracy, speed, and reproducibility are critical. Using only 1–2 µL of sample and no cuvette, it rapidly measures the concentration and purity of DNA, RNA, and proteins. With user-friendly software and automatic calculation of A260/A280 and A260/A230 ratios, it delivers reliable sample QC in just a few seconds. Pro Drop is an ideal choice for PCR and Real-Time PCR laboratories, sequencing workflows, and diagnostic centers that require stable results alongside easy operation and local technical support.
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The Denagene Tajhiz Pro Drop is a UV-Vis microvolume spectrophotometer for fast and accurate quantification and purity assessment of DNA, RNA, and proteins. It provides essential QC information in a short time using only 1–2 µL of sample—without the need for cuvettes.

In Pro Drop, the sample is placed on a pedestal. After closing the arm, a liquid column is formed in the optical path. The pathlength is automatically adjusted from 1.0 to 0.2 mm, enabling measurement of both dilute and highly concentrated samples—often without dilution. Spectral analysis is performed using a 3648-element linear CCD array.

The key difference between Pro Drop and Eco Drop (and many entry-level systems) is the pulsed xenon flash lamp light source, making Pro Drop a better fit for users who demand higher accuracy, repeatability, and measurement stability—especially in diagnostic applications and critical projects.

Key Technical Specifications (Pro Drop)

  • Light source: Pulsed xenon flash lamp
  • Sample volume: 1–2 µL (cuvette-free)
  • Optical pathlength: 1.0 mm with auto-ranging down to 0.2 mm
  • Wavelength range: 320–700 nm
  • Wavelength accuracy: < 0.7 nm
  • Spectral resolution: 2.5 nm (FWHM at 546 nm)
  • Absorbance precision: 0.003 Abs
  • 10 mm-equivalent absorbance range: 0.02–75 Abs
  • dsDNA limit of detection: 2 ng/µL
  • Maximum dsDNA concentration: 3700 ng/µL
  • Measurement cycle time: ~2 seconds
  • Dimensions / weight: 25 × 25 × 25 cm / 3.5 kg
  • Pedestal material: 303 stainless steel and quartz fiber
  • Power: 220 V, 50 Hz / ~30 W

Advantages vs. Conventional Spectrophotometers

  • Ultra-low sample volume: only 1–2 µL (traditional systems typically require cuvettes and larger volumes)
  • High speed: suitable for routine workflows and high sample numbers
  • Cuvette-free operation: reduces consumable cost and minimizes errors related to cuvette handling/cleaning
  • Auto-ranging pathlength: enables measurement of concentrated samples with less need for dilution
  • Improved reproducibility: xenon flash lamp supports stable, repeatable measurements for precision-focused labs

Pro Drop Applications in Molecular & Diagnostic Laboratories

  • DNA/RNA QC before PCR, Real-Time PCR, and RT-PCR
  • Concentration measurement of genomic DNA, plasmid DNA, and cDNA
  • Sample quality monitoring prior to sequencing and cloning workflows
  • Protein quantification and QC of UV-Vis solutions
  • Suitable for clinical diagnostics, genetics, virology, and research laboratories

Pro Drop Maintenance & Calibration

  • Clean the pedestal after each sample using a lint-free tissue and distilled water/ethanol
  • Blank with the same buffer/solvent used for the sample to minimize baseline error
  • Keep the system in a dry, dust-free, vibration-free environment
  • Perform periodic calibration according to company recommendations and internal lab standards

Buying Guide for Denagene Tajhiz Pro Drop

Before choosing between Eco Drop and Pro Drop, consider:

  • Daily workload: high sample volume makes speed and measurement stability more important
  • Application type: DNA/RNA only, or also proteins and OD600?
  • Need for higher accuracy and speed: Pro Drop with a xenon flash lamp is better for users sensitive to accuracy and repeatability
  • Data storage and export: USB output and connectivity simplify reporting and documentation

Denagene Tajhiz experts can recommend the best option (Eco Drop or Pro Drop) based on test type, sample volume, and budget. In-country installation, training, support, and periodic calibration services are also available.

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Technical Specification
Specification Eco Drop Pro Drop
Light source LED Xenon flash lamp
Sample volume (µL) 1–2 1–2
Optical pathlength (mm) 1.0 (auto-ranging down to 0.2) 1.0 (auto-ranging down to 0.2)
Detector 3648-element linear silicon CCD array 3648-element linear silicon CCD array
Wavelength range (nm) 260–280 and 360–600 220–700
Wavelength accuracy (nm) < 0.7 < 0.7
Spectral resolution (FWHM at 546 nm) 2.5 nm 2.5 nm
Absorbance precision (1 mm path) 0.003 Abs 0.003 Abs
Absorbance accuracy (at Abs 0.76, 257 nm) 2% 2%
Absorbance range (10 mm equivalent) 0.02–75 Abs 0.02–75 Abs
dsDNA limit of detection 2 ng/µL 2 ng/µL
Max dsDNA concentration 3700 ng/µL 3700 ng/µL
Measurement cycle time (s) 10 2
Dimensions (cm) 25 × 25 × 25 25 × 25 × 25
Weight (kg) 3.5 3.5
Pedestal material 303 stainless steel & quartz fiber 303 stainless steel & quartz fiber
Operating voltage 220 V, 50 Hz 220 V, 50 Hz
Power consumption (W) 30 30
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    Tutorial Video

    FAQ

    What sample types can the DeNA EXT process?

    It supports a wide range of samples, including whole blood, serum/plasma, swabs, cells, homogenized tissue, and common viral/bacterial specimens (depending on the selected kit and protocol).

    How many samples can it run at once and how long does a run take?

    The DeNA EXT processes 1–32 samples per run (32-test model). Typical extraction time is 10–30 minutes, depending on the protocol.

    Does it support custom protocols and different extraction kits?

    Yes. The system comes with 20 pre-set protocols and also supports defining new/custom protocols, allowing compatibility with various kits and workflows.

    How does it reduce contamination and improve consistency compared to manual extraction?

    It performs extraction in an automated workflow with auto-calibration before each run, minimizing operator-dependent variation and reducing the risk of handling-related errors and cross-contamination.
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